Subakute sklerosierende Panenzephalitis (SSPE)

Blocking Factors in Sspe Patients

Since the description of a case with "diffuse encephalitis with sclerosing inflammation of the hemisphere white matter" by Bodechtel and Guttman (1), there have been numerous reports that have indicated that measles virus is associated with this disease. Subacute sclerosing panencephalitis (SSPE) I occurs mostly in children and young adults as a slow progressive inflammatory disorder of the cen...

Subacute Sclerosing Panencephalitis (SSPE) - due to Lack of Complete Immunization?

The child was admitted in the paediatric department with complaints of fits for one month and altered level of consciousness for two days prior to admission. Mother had also noticed changes in behaviour for one month. He became unusually frightened when he was alone and in a dark room. Fits were not controlled for two days when he came to Abbasi Shaheed hospital and child became drowsy. He was ...

Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection.

A 13-month-old male presented with repetitive episodes of myoclonic jerks of the head and extremities for two months. His past medical history revealed that his non-immunized mother had measles at the time of delivery. Measles antibody titers in serum and cerebrospinal fluid (CSF) were 1/512 (hemagglutinin inhibition [HI]) and 1/128 HI, respectively. Immunofixation electrophoresis of CSF reveal...

Subacute Sclerosing Pan-Encephalitis (SSPE) – Past and Present

Subacute Scerosing Pan Encephalitis (SSPE), a devastating brain disease of young children was frequently taken into account in the differential diagnosis of the so-called "neurodegenerative diseases of childhood" by paediatricians, child neurologist and psychiatrists during the second half of the last century. Fortunately, this diagnosis is considered very rarely today in well developed countri...

The occurrence of SSPE in Iran